The good news is that my myeloma is growing only very slowly, with a Mayo Clinic labeling index of 0.2, described as a "VERY LOW proliferative rate" (their emphasis). For anyone with myeloma this is very good news and cause for a lot of hope, for both the short and the long term. Dr. Lacy said that a person with this labeling index can expect to live a long time with myeloma. I didn't press her to quantify that, because we all know that the doctors can't give us hard numbers on our survival.
I will digest the results more and post again in a day or two, but here are some highlights. Bad stuff:
- In two months, M-spike jumped from 2.05 to 2.7 g/dL. I suspect (and hope) that some of this jump is due to a difference in testing - this is my first-ever set of labs from Mayo.
- Calcium, Beta-2 microglobulin, and lambda free light chains are all up from two months ago and all higher than they should be.
- Most sinister: The PET scan clearly shows three very active regions in my bones: one in each shoulder blade, and one in the T10 thoracic vertebrae midway between the waist and the shoulder.
- Platelets, red blood cell count, hemoglobin, creatinine, and albumin are all well within the normal range.
- Same with LDH and C-reactive protein.
- IgG is the same as the last test at MOHPA, suggesting that the M-spike may not really have changed as much as the numbers indicate.
- No abnormal proteins were found in the 24-hour urine.
- Revlimid with low-dose dexamethasone (a steroid), or
- A phase-II trial of a brand-new not-yet-approved drug with the code name CC-4047. This is a new Celgene drug, intended to be an improvement on Revlimid, which itself is an improvement on thalidomide. This too would be taken with dexamethasone.
When the drug-trial coordinator asked Dr. Lacy how soon I should start, she replied "yesterday!" Since then I have taken an EKG and had another full x-ray bone survey, and I will see her again tomorrow to wrap things up and start the trial.
Dex tomorrow night. Oh my.
Today's lunch before traveling to Mayo: Papaya, pineapple, organic medjool dates, pistachios, orange, organic fat-free yogurt.