Serum Cancer Markers:
My myeloma is IgG Lambda, a very common type. So far, the tumor burden seems to be quantifiable by measuring its surrogates, the IgG protein level and the M-spike. IgG is down from 1150 mg/dL last month to 1020 this time. Accordingly, M-spike is down from 1.1 to 1.0 g/dL. Light chains are basically unchanged. Liver enzymes are up a bit, but that could be from running a marathon four days ago - they're still within the reference range.
Last month my calcium was 10.5 mg/dL, which is significantly above the top of the reference range. Doctor LH recommended that I cut my daily Vitamin D3 supplementation in half, to 2500 IU, and I did. This month calcium was 10.0 mg/dL, just below the top of the reference range. Calcium in the blood has varied quite a lot from month to month, so we can't say for sure that the Vitamin D3 reduction made any difference, but it might have. There is such a thing as too much Vitamin D, although 5000 IU/day is far below the levels generally thought to be harmful. That threshhold might change, however, when the supplement is taken for years, as I have done.
Too much calcium in the blood can be harmful in itself, playing a part in atherosclerosis, but for a myelomiac it can also be a signal of bone loss, indicating that the myeloma is active in the marrow of some bone or bones. I'm glad that it went down, and for now I'll stay on the reduced amount of Vitamin D3.
Even though the calcium level went down, though, it's still on the high side of normal. Considering that it's been 18 months since the last skeletal survey, Dr RH thought it would be reasonable to have one, and scheduled it as part of next month's tests. That's a proactive approach that I appreciate. I did have a clear PET scan six months ago, but myeloma can be very sneaky.
Some Current Test Results:
|Test||Jun 30||Jul 28||Aug 25||Sep 22||Remarks|
|M-spike g/dL||1.0||1.0||1.1||1.0||\ Tumor marker|
|IgG mg/dL||1070||1030||1150||1020||/ Tumor marker|
|Lambda mg/dL||1.74||2.21||2.25||2.49||L Free light chains|
|Creatinine mg/dL||1.3||1.3||1.1||0.9||Kidney, good|
|HGB g/dL||14.8||15.1||14.7||14.9||Hemoglobin, OK|
|RBC M/uL||4.28||4.17||4.08||4.09||Red cells, low|
|WBC K/uL||3.6||5.1||3.8||6.2||White cells, normal|
|ANC K/uL||1.17||1.90||1.40||2.60||Neutrophils, normal|
|My Myeloma||A discussion of my myeloma, not very technical.|
|My Treatment History||Not technical.|
|My Test Charts||Graphic displays of several key test results over time.|
|My Test Result Table||Somewhat technical. Best with a wide browser window.|
|My Supplement Regimen||With links to where I buy them.|
Presque Isle State Park, September 18, 2011, a view of Lake Erie from along the marathon route: