The decline of 3% in M-spike is probably well within the margin of repeatability of that test, but at least it suggests that monoclonal proteins did not go UP. I do not know of any reason why the normal IgG should have gone up - I was not dealing with any kind of infection that I know of on blood-draw day - but of course it could be due to a transient subclinical infection of some kind. Perhaps the myeloma is not marching; we shall see in five weeks or beyond.
Meantime I will:
- Continue with the curcumin,
- Add low-dose naltrexone,
- Add resveratrol and perhaps more,
- Get the bone survey (I had a skull MRI done in April),
- Look into the new Life Extension Curcumin and perhaps use that for part of my daily dose,
- Examine the Mayo mSMART concensus protocol more carefully (I believe that this will indicate that I should not treat conventionally until CRAB symptoms appear), and
- Think long and hard about treatment philosophy when and if conventional treatment really is necessary.
In answer to other very good questions:
- The doctor said that some calcium is bound in the IgG, so the calcium measurement in the normal Chem-20 panel would naturally rise with the IgG and might not be a separate indicator. In five weeks he will order another test for what I believe he called "free calcium," which will be more definitive.
- I did not ask about vitamin D but I do take 1000 IU daily, or is it 2000?
- I have had a thyroid test (T4 and another) which were normal. However, my primary physician thinks I neverhteless have the beginning of a goiter (!), so that is a concern and I have started taking a thyroid supplement which includes bovine tissue.
- I will ask my doctor about another cranial or spinal MRI.
- My onc just didn't order the B2M test, for some reason. Since it was also trending up I think he should have, and he said that will be included in five weeks, along with the extra calcium test.
- I've had three BMB's so far, with the most-recent showing only 6.8% plasma cells. However, all three biopsies are from the same hip; next time I will switch hips!
- I'll check into PET as well.