My friend Max put me onto low-dose naltrexone (LDN) some time ago. I blogged about it in June. It is a prescription drug approved for treatment of drug addiction, but used by a few doctors for cancer and other maladies, off-label and in small doses. It is thought to work by stimulating the body's endorphins back to normal levels, thereby restoring the body's immune system.
Long story short: Max called today to report his own results: IgM was over 3000 (normal is 300) and has DROPPED 18% in four and a half months on LDN. Max is not an excitable person, but he certainly did sound pleased with this result.
To be sure, an 18% reduction in IgM could be just a normal variation, or almost so, a combination of variability in the test and actual variability in his blood. Though his doctor seemed underwhelmed, Max thinks this was an actual drop, because his numbers had been steadily climbing by about that amount at every test interval. The future will reveal the truth, of course.
Max does NOT have myeloma; he has Waldenstrom's Macroglobulinemia (what a mouthful). Whereas myeloma patients normally talk about IgG or IgA, his naughty protein is IgM; it affects the body somewhat differently and is treated somewhat differently. If he had myeloma instead, who knows whether he would have experienced this benefit from LDN?
Hoping that it can, I am taking LDN too, for the past eleven days, along with curcumin, quercetin, resveratrol, mostly-vegetarian diet and the kitchen sink.